Background.We conducted a validation study of digital pathology for the quantitative assessment of tissue-based biomarkers with immunohistochemistry.Objective.To examine observer agreement as a function of viewing modality (digital versus Staging optical microscopy), whole slide versus tissue microarray (TMA) review, biomarker type (HER2 incorporat
Plant senescence is a critical life history process accompanied by chlorophyll degradation and has large implications for nutrient resorption and carbohydrate storage.Although photoperiod governs much of seasonal leaf senescence in many plant species, temperature has also been shown to modulate this process.Therefore, we hypothesized that climate w
The purpose of this study is to provide a model for measuring the moral hazard of managers based on financial data in firms listed in Tehran Stock Exchange.For this purpose, based on the literature, theories and surveys, 22 variables are extracted as sources of management moral hazards and they are and re-exposed to the comments of experts in order
Background: Primary care in remote communities in northern Canada is delivered primarily by nurses who receive clinical support from physicians in regional centres Right Seat Adjustment Lever and the patient transportation system.To improve continuity, quality and access to care in remote northern communities, it is important to understand the pers
Abstract The science of science has attracted growing research interests, partly due to the increasing availability of large-scale datasets capturing the innerworkings of science.These datasets, and the numerous linkages among them, enable researchers to ask a range of fascinating questions about how science works and where innovation occurs.Yet as